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December 2025: Ascletis Pharma announced that ASC30, an oral small-molecule GLP-1 receptor agonist, demonstrated 7.7% placebo-adjusted weight loss in a 13-week U.S

Sources: Wang X, et al

The T cells were then cocultured with NY-ESO-1 and A375 tumor cells in a 3:1 ratio for 24 h before labeling with BMP for 2 h (Fig

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However, Wegovy continues to receive coverage for two specific FDA-approved indications beyond general weight management